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Agencia Estatal Consejo Superior de Investigaciones Científicas

Instituto de Parasitología y Biomedicina López-Neyra, CSIC, is devoted to research in the area of genetics, immunology, and molecular biology of important world-wide biomedical problems.

Role within 3TR

CSIC will participate in work packages 1 (Data Management) and 4 (Profiling & Systems Biology / Data Integration Group). It will genotype data using high density SNPs arrays and whole genome sequencing to identify modifications in risk-associated eQTLs and meQTLs. In Addition, CSIC will use chromosome conformation capture based technology (CHi-C) to gain insight into the interactions of non-coding autoimmunity/inflammatory risk loci and their transcriptional targets, confirming causal genes and their gene expression regulation.